Returned Favor Leads to New Care

New litigation limit leads to storage woes.

An Old Insight Leads to New Tools

seems an unlikely person to help transform the statistical rigor of experiments in the vanguard of microarray analyses and proteomics. For one thing, he died almost 250 years ago in Tunbridge Wells, an English town that remains sleepy even today. And rather than being a scientist, Bayes was a nonconformist minister. Yet today's microarray and proteomic researchers increasingly use the statistic...

Transcription Blockage Leads to New Beginnings

Environmental agents are constantly challenging cells by damaging DNA, leading to the blockage of transcription elongation. How do cells deal with transcription-blockage and how is transcription restarted after the blocking lesions are removed? Here we review the processes responsible for the removal of transcription-blocking lesions, as well as mechanisms of transcription restart. We also disc...

Joint action between child health care nurses and midwives leads to continuity of care for expectant and new mothers

Reduction of the duration of postpartum hospital stay in western countries highlights the need for better support and continuity of care for expectant and new mothers. The aim of this study was to investigate strategies to improve continuity of care for expectant and new mothers. The study also aimed to elaborate on a preliminary substantive grounded theory model of "linkage in the chain of car...

Novel Bi-allelic PDE6C Variant Leads to Congenital Achromatopsia

Background: The clinical phenotyping of patients with achromatopsia harboring variants in phosphordiesterase 6C (PDE6C) has poorly been described in the literature. PDE6C encodes the catalytic subunit of the cone phosphodiesterase, which hydrolyzes the cyclic guanosine monophosphate that proceeds with the hyperpolarization of photoreceptor cell membranes, as the final step of the phototransduct...